Neurological soft signs in obsessive-compulsive disorder: two empirical studies and meta-analysis

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Neurological soft signs in obsessive-compulsive disorder: two empirical studies and meta-analysis.

BACKGROUND Neurological soft signs (NSS) have been inconsistently reported in obsessive-compulsive disorder (OCD) but may make an impact on treatment response. Method The current study examined the presence of NSS in two independent European samples of OCD patients (combined 85 patients and 88 matched healthy controls) using a standardized instrument and conducted a meta-analysis of all publish...

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Neurological soft signs in obsessive-compulsive disorder.

BACKGROUND Neurological soft signs (NSSs) are defined as abnormal motor or sensory findings, including involuntary movements, a variety of dispraxia, difficulties in performing rapid alternating movements, difficulties in two-point discrimination, and graphesthesia in a person without a neurological disorder which can be determined as its focus. AIMS to investigate the relationship of NSSs wi...

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Neurological soft signs in early stage of schizophrenia associated with obsessive-compulsive disorder

BACKGROUND Given that the obsessive-compulsive disorder (OCD) occurs with a much higher frequency in schizophrenia than in the general population, and, both schizophrenia and OCD are presumed to be neurodevelopmental disorders, the hypothesis of a distinct subtype of schizophrenia, the "schizo-obsessive" one, was raised. AIM Considering the neurological soft signs as neurobiological markers i...

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Neurological examination in obsessive-compulsive disorder.

Recent studies suggest the occurrence of a neurological dysfunction in Obsessive-Compulsive Disorder (OCD). The purpose of the present study was to verify the clinical value of a neurological evaluation in patients with the disease. We submitted 15 patients with OCD (five of whom were under clomipramine) and 15 controls in a detailed neurological examination, including assessment of the neurolo...

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Comparative Study of Neurological Soft Signs in Patients with Schizophrenia or Obsessive-compulsive Disorder, and Healthy Controls.

OBJECTIVE The primary objective of this study was to examine neurological soft signs in patients with obsessive-compulsive disorder compared with patients with schizophrenia and a control group in the Indian setting. The secondary objective was to find any correlation between age at onset and neurological soft signs scores, as well as that between severity of obsessive-compulsive disorder sympt...

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ژورنال

عنوان ژورنال: Psychological Medicine

سال: 2012

ISSN: 0033-2917,1469-8978

DOI: 10.1017/s0033291712002012