Neuroinflammation in Tinnitus

Abstract Purpose of Review The current review aims to explore recent studies that have illustrated a link between neuroinflammation and tinnitus the consequential effect on neuronal functioning. We parallels amongst pain pathologies novel treatment option. Recent Findings Genetic pharmacological blockage pro-inflammatory cytokines mitigates physiological behavioral phenotype in acute rodent models. In addition, target signaling pathway prevent transition from chronic neuropathic pain, which could translate tinnitus. Summary Neuroinflammation likely mediates hyperexcitability auditory pathway, driving development tinnitus, we believe translational regulation plays role maintaining persistent signaling. therefore propose this as potential therapeutic strategy.