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The dramatic increasing prevalence of autism spectrum disorders (ASDs) (1), together with the influence on the quality of life and the lifetime societal cost of caring, has called for newest research on both the development of these diseases and the therapeutic options. Nowadays, it is well recognized that multifactorial and polygenic features (complex combination of genetic, epigenetic, and en...
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Autism spectrum disorder (ASD) involves a complex interplay of both genetic and environmental risk factors, with immune alterations and synaptic connection deficiency in early life. In the past decade, studies of ASD have substantially increased, in both humans and animal models. Immunological imbalance (including autoimmunity) has been proposed as a major etiological component in ASD, taking i...
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Comfort, W.W. and J. van Mill, Some topological groups with, and some without, proper dense subgroups, Topology and its Applications 41 (1991) 3-15. Continuing earlier investigations into the question cf the existence of a proper dense subgroup of a given topological group, the authors obtain some positive and some negative results, as follows: (a) Every non-degenerate connected Abelian group c...
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ژورنال
عنوان ژورنال: Gut
سال: 2000
ISSN: 0017-5749
DOI: 10.1136/gut.47.suppl_4.iv63