منابع مشابه
Neurogenic influences in arthritis.
Pain is a pivotal symptom faced by patients with rheumatic disease. Nevertheless, mechanisms of articular pain remain unclear and there is little correlation between pain, disability, and radiological change. ' Although a protective function for the pain sensory system has long been assumed, Wall and others have suggested that the system may also function to modify local responses to tissue tra...
متن کاملAntiinflammatory Influences of wMSH Molecules: Central Neurogenic and Peripheral Actions
cu-Melanocyte-stimulating hormone (a-MSH,.,,) and its COOHterminal tripeptide ol-MSH,,.,, (Lys Pro Val) inhibit inflammation when administered systemically. Recent evidence indicates that c~-MSH,.,, can likewise inhibit inflammation in the skin solely via an action within the brain. Because of the potential importance of this discovery to understanding the control of inflammation and because (u...
متن کاملArthritis and Pain. Neurogenic origin of joint pain
Arthritis pain affects millions of people worldwide yet we still have only a limited understanding of what makes our joints ache. This review examines the sensory innervation of diarthroidal joints and discusses the neurophysiological processes that lead to the generation of painful sensation. During inflammation, joint nerves become sensitized to mechanical stimuli through the actions of neuro...
متن کاملGenetic Influences on Treatment Response in Rheumatoid Arthritis
The lack of clinical and laboratory markers that reliably predict response, side effects, or toxicity to therapeutic intervention poses a significant challenge in therapeutic decision-making. Consequently, rheumatologists and other physicians treating patients with rheumatoid arthritis (RA) must choose treatment regimens based on their own experience and assessment of the literature which usual...
متن کاملComparing bone mineral density in rheumatoid arthritis and psoriatic arthritis
Background: Changes in patients’ bone mineral density (BMD) is one of the problems in patients with rheumatoid arthritis, which can be due to the use of corticosteroid drugs to reduce patients' symptoms or due to the aging process in patients. In this study, we decided to compare BMD in patients with psoriatic arthritis and rheumatoid arthritis. Methods: This study as a cross-sectional descrip...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1990
ISSN: 0003-4967
DOI: 10.1136/ard.49.8.649