Neurofilament is superior to cytokeratin 20 in supporting cutaneous origin for neuroendocrine carcinoma

Mediastinal Neuroendocrine Carcinoma of Unknown Origin Presenting with Superior Vena Cava Syndrome (SVCS): A Case Report

Primary neuroendocrine carcinoma (NEC) of the mediastinum is a rare type of carcinoma. According to the literature, only five cases of this condition have been reported so far. In this paper, we present a rare case of mediastinal NEC of unknown primary site. The patient was a 34-year-old man with mediastinal NEC, who presented with chronic dry cough and a right-sided mediastinal mass one year p...

Primary cutaneous signet ring cell carcinoma expressing cytokeratin 20 immunoreactivity.

Primary cutaneous signet ring cell carcinoma (PCSRCC) is a very unusual but distinctive clinicopathologic entity that can simulate metastatic adenocarcinomas. It is defined as a diffuse malignant epithelial neoplasia localized in the dermis and subcutis without epidermal involvement, showing variable amounts of signet ring cells, without evidence of visceral adenocarcinoma. We present 2 cases o...

mediastinal neuroendocrine carcinoma of unknown origin presenting with superior vena cava syndrome (svcs): a case report

primary neuroendocrine carcinoma (nec) of the mediastinum is a rare type of carcinoma. according to the literature, only five cases of this condition have been reported so far. in this paper, we present a rare case of mediastinal nec of unknown primary site. the patient was a 34-year-old man with mediastinal nec, who presented with chronic dry cough and a right-sided mediastinal mass one year p...

Cytokeratin 20-positive hepatocellular carcinoma

The differential diagnosis between hepatocellular carcinoma (HCC), cholangiocarcinoma (CC) and metastatic colorectal adenocarcinoma (MCA) may be difficult when only based on morphology. For this purpose immunohistochemical analyses are often required, utilizing antibodies directed against CK8-18, Hep-Par1, glypican 3, CK7, CK19, CK20. Here we report a case of a 65-year-old man who presented wit...

Primary Cutaneous Neuroendocrine Carcinoma , Merkel Cell Carcinoma .