Neuroendocrine control of the sympathetic nervous system in obesity
نویسندگان
چکیده
منابع مشابه
Role of sympathetic nervous system and neuropeptides in obesity hypertension.
Obesity is the most common cause of human essential hypertension in most industrialized countries. Although the precise mechanisms of obesity hypertension are not fully understood, considerable evidence suggests that excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role. Sympathetic activation appears to mediate at least part of the obesity-induced ...
متن کاملRelation of obesity and diet to sympathetic nervous system activity.
The hypothesis that dietary intake and obesity stimulate the sympathetic nervous system was investigated in a cross-sectional study of 572 men aged 43-85 years from the Normative Aging Study. Habitus was represented by body mass index, as a measure of overall adiposity, and by the ratio of abdomen-to-hip circumference (abdomen/hip ratio), as a measure of centripetal fat distribution. Sympatheti...
متن کاملA sympathetic nervous system evaluation of obesity stigma
The portrayal of obesity in the media is often one of negativity. Consequently, it may generate an increase in stigma. Obesity stigma, a form of social discrimination, is responsible for many of the negative psychological and physiological effects on individual wellness. These effects not only impact individual health, but also affect the economy, and ultimately, societal wellness. In an attemp...
متن کاملSympathetic nervous system neuroplasticity.
In human and experimental models of heart failure there is widespread change in the sympathetic nervous system. This involves preferential activation of the sympathetic nervous outflow to the heart, impairment of norepinephrine reuptake by sympathetic nerves, and reduction of the content of norepinephrine in the failing myocardium, attributable in part to sympathetic neuronal rarefaction.1–4 Mi...
متن کاملRole of the sympathetic nervous system during the development of obesity-induced hypertension in rabbits.
We have previously reported that weight gain induced by high-fat diet (HFD) leads to an increase in mean arterial pressure (MAP, +14%) and heart rate (HR, +31%) in the adult rabbit. In the present study, we tested the hypothesis that an increased activity of the sympathetic nervous system may contribute to the development of obesity-induced hypertension. A combination of alpha- and beta-adrener...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Obesity and metabolism
سال: 2014
ISSN: 2306-5524,2071-8713
DOI: 10.14341/omet2014462-63