Neurodevelopmental Effects of Antiepileptic Drugs
نویسندگان
چکیده
منابع مشابه
Cognitive Effects of Antiepileptic Drugs
Antiepileptic drugs (AEDs) can adversely affect cognitive function by suppressing neuronal excitability or enhancing inhibitory neurotransmission. The main cognitive effects of AEDs are impaired attention, vigilance, and psychomotor speed, but secondary effects can manifest on other cognitive functions. Although the long-term use of AEDs can obviously elicit cognitive dysfunction in epilepsy pa...
متن کاملTeratogenic effects of antiepileptic drugs
The use of older generation antiepileptic drugs (AEDs) during pregnancy is known to be associated with a two- to threefold increased risk of birth defects in the offspring and possible also other adverse outcomes in the exposed infant. Much less has been known about newer generation AEDs in this respect. Recent studies based on national registries as well as specific epilepsy and pregnancy regi...
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Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...
متن کاملCognitive side effects of antiepileptic drugs.
All of the established antiepileptic drugs (AEDs) can produce cognitive side effects, which are increased with polypharmacy and with increasing dosage and anticonvulsant blood levels. However, cognitive side effects are usually modest for AED monotherapy with anticonvulsant blood levels within the standard therapeutic ranges. Further, these effects are offset in part by reduced seizure activity...
متن کاملReproductive endocrine side effects of antiepileptic drugs
RATIONALE: There is a complex interplay between epilepsy, antiepileptic drugs, and reproductive endocrine disorders. Epilepsy itself may influence on the hormonal balance, hormones may affect epilepsy, hormones may influence on the efficacy and metabolism of antiepileptic drugs and antiepileptic drugs may alter the hormone levels.To better understand the interaction of antiepileptic drugs and p...
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ژورنال
عنوان ژورنال: Neurochemical Research
سال: 2017
ISSN: 0364-3190,1573-6903
DOI: 10.1007/s11064-017-2262-4