Neurocognitive deficits in schizophrenia are likely to be less severe and less related to the disorder than previously thought

Younger Genes Are Less Likely to Be Essential than Older Genes, and Duplicates Are Less Likely to Be Essential than Singletons of the Same Age

Recently duplicated genes are believed to often overlap in function and expression. A priori, they are thus less likely to be essential. Although this was indeed observed in yeast, mouse singletons and duplicates were reported to be equally often essential. This contradiction can only partly be explained by experimental biases. We herein show that older genes (i.e., genes with earlier phyletic ...

Why women are less likely than men to commit suicide.

Major depression forms the background of upwards of half of all suicides. Women are twice as likely as men to experience major depression, yet women are one fourth as likely as men to take their own lives. Current and past explanations of this paradox are built on androcentric assumptions that women are deficient in some way. The reverse may be true where suicide is concerned. Men value indepen...

The joint flanker effect: less social than previously thought.

Research on joint action has been taken to suggest that actors automatically co-represent the tasks and/or actions of co-actors. However, recent findings on the joint Simon effect have provided evidence for a nonsocial account, which renders automatic co-representation unlikely. In the present study, we aimed to test whether a nonsocial account is also feasible for the joint version of the flan...

Severe Ketoacidosis (pH ≤ 6.9) in Type 2 Diabetes: More Frequent and Less Ominous Than Previously Thought

Diabetic ketoacidosis is a life-threatening acute metabolic complication of uncontrolled diabetes. Severe cases of DKA (pH ≤ 7.00, bicarbonate level ≤ 10.0, anion gap > 12, positive ketones, and altered mental status) are commonly encountered in patients with type 1 diabetes and are thought to carry an ominous prognosis. There is not enough information on the clinical course of severely acidoti...

Review: St John's Wort may be less effective than previously thought in people with depression.