"Neuro-Sweet Disease"

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Neuro-neutrophilic disease: neuro-Behçet disease and neuro-Sweet disease.

“Neuro-Sweet disease (NSD)” was proposed as a distinct entity of encephalomeningitis in 1999 (1). Sweet disease has been considered as a multisystem inflammatory disorder characterized by painful erythematous plaques, and has been classified as a dermatologic disease. The plaques respond to systemic corticosteroids, and heal without scarring. It has been disclosed that aseptic neutrophilic infl...

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"Neuro-sweet disease": benign recurrent encephalitis with neutrophilic dermatosis.

OBJECTIVE To describe benign recurrent encephalitis in a case of Sweet syndrome that also showed clinical features of Behçet disease. CASE REPORT A 37-year-old Japanese man developed relapsing and remitting encephalitis and mucocutaneous symptoms mimicking Behçet disease. Magnetic resonance images showed at least 5 episodes of transient abnormal signal intensity in various cerebral regions ov...

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Abnormalities on Brain Susceptibility-weighted Imaging in Neuro-Sweet Disease

An 81-year-old woman presented with a one-week history of pyrexia (38.6°C), headache, acalculia, and hemianopia. Laboratory examinations revealed an elevated leukocyte count (10,000/mm), neutrophil count (8,200/mm), and erythrocyte sedimentation rate (43 mm/h). CSF study revealed pleocytosis (33/mm) and an elevated protein level (402 mg/dL). MRI showed leptomeningeal gadolinium enhancement (arr...

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Two cases of possible neuro-Sweet disease with meningoencephalitis as the initial manifestation

We report 2 cases that were considered to be neuro-Sweet disease. They initially manifested with meningoencephalitis and no skin lesions, and rapidly improved with corticosteroid therapy. In both cases, patients complained of meningitic symptoms such as fever and headache, and HLA-B54 and -Cw1 turned out to be positive over the clinical course. Cerebrospinal fluid analysis showed increased leve...

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Neuro-Sweet disease with positive modified acid-fast staining of the cerebrospinal fluid: A case report.

Neuro-Sweet disease (NSD) is Sweet disease with central nervous system (CNS) involvement. To the best of our knowledge, the present case report is the first to describe NSD complicated by endogenous infection with Mycobacterium tuberculosis. The present case report describes a male patient who developed NSD-induced meningitis, which initially manifested as a fever, headache and neck stiffness. ...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 1999

ISSN: 0003-9942

DOI: 10.1001/archneur.56.8.1010