Neural stem cells for diabetes cell‐based therapy
نویسندگان
چکیده
منابع مشابه
Neural stem cells for diabetes cell-based therapy
» Isolation and cultivation of pancreas stem cells as renewable sources of beta cells would be a major breakthrough. . . « Diabetes mellitus is a disorder resulting from lack of either production or action of insulin signalling. It affects more than 200 million people worldwide. There is no cure for diabetes and the patients rely on exogenous supply of insulin and/or oral use of hypoglycemic su...
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In this article, we have reviewed the developments of studies of stem cells therapy for type 1 diabetes since this century. Review of the literature was based on computer searches (PubMed) and our studies. Type 1 diabetes can now be ameliorated by islet transplantation, but this treatment is restricted by the scarcity of islet tissue. Hopes for a limitless supply of a substitute for primary isl...
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متن کاملStem Cells Therapy in Diabetes Mellitus
Abbreviations: BMSCs: Bone Marrow-derived Stem Cells; c-MYC: Myc Proto-oncogene Protein; CXCr: CXC-Chemokine Receptor; DE: Definitive Endoderm; DPP4: Dipeptidyl Peptidase 4; EB: Embryoid Body; EGF: Epidermal Growth Factor; ES: Embryonic Stem; ESCs: Embryonic Stem Cells; FACS: Fluorescence-activated Cell Sorting; FGF: Fibroblast Growth Factor; FoXa2: Forkhead Box Protein A2; GLP1: Glucagon-like ...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2011
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.201100178