Neural mechanism of stimulant-induced psychosis: secondary brain damage following methamphetamine dependence.
نویسندگان
چکیده
منابع مشابه
PM293. Efficacy and Safety of Aripiprazole for Maintenance Treatment of Methamphetamine Dependence Following Methamphetamine Psychosis: A Naturalistic Retrospective Study
The problem of new psychoactive substances is emerging globally. Cannabinoid receptors mediate the action of synthetic cannabinoids, which are one of most abused drugs. Recently, cannabinoid receptors 1 (CB1R) have been reported to silence glutamatergic nerve terminals in cerebellar granule cells via synaptic vesicle redistribution. This study aimed to determine whether synthetic cannabinoid ad...
متن کاملThe neurobiology of methamphetamine induced psychosis
Chronic methamphetamine abuse commonly leads to psychosis, with positive and cognitive symptoms that are similar to those of schizophrenia. Methamphetamine induced psychosis (MAP) can persist and diagnoses of MAP often change to a diagnosis of schizophrenia over time. Studies in schizophrenia have found much evidence of cortical GABAergic dysfunction. Methamphetamine psychosis is a well studied...
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Methamphetamine (METH) abuse causes serious health problems worldwide, and long-term use of METH disrupts the blood-brain barrier (BBB). Herein, we explored the potential mechanism of endoplasmic reticulum (ER) stress in METH-induced BBB endothelial cell damage in vitro and the therapeutic potential of endoplasmic reticulum stress inhibitors for METH-induced BBB disruption in C57BL/6J mice. Exp...
متن کاملTreating Methamphetamine-Induced Resistant Psychosis with Clozapine
Background. Methamphetamine-induced psychosis (MIP) in Iran has turned into a serious issue in terms of health and treatment, lacking any obvious treatment methods for its resistant cases. Aims of Case Report. In the present study, a number of two cases of treatment of MIP with clozapine, which were resistant to the treatment with other antipsychotics, have been reported. Both cases completely ...
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Abstract Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia. Case Report: This article reports a patient with tramadol dependency that had psychosis after tramadol withdrawal. Conclusion: By the increase of tramadol usage for relief of chronic pain, t...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1994
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)49938-1