Neural Differentiation of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells
نویسندگان
چکیده
منابع مشابه
A New Two Step Induction Protocol for Neural Differentiation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells
Background: In this study, we examined a new two step induction protocol for improving the differentiation of human umbilical cord blood-derived mesenchymal stem cells into neural progenitor cells. Materials and Methods: Human umbilical cord blood-derived mesenchymal stem cells were first cultured in Dulbecco’s modified eagle medium supplemented with 10% fetal bovine serum in a humidified incu...
متن کاملneural differentiation of human umbilical cord blood-derived mesenchymal stem cells
conclusions taken together, the combination of chemical and growth factors in the two-step induction protocol may improve the efficiency of msc differentiation into neural progenitor cells, and may be a new method for the easy and fast application of mscs in regenerative medicine in the future. results the results of real-time pcr showed that the expression of the gfap, mbp, and map-2 genes aft...
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Background: Stem cell therapy for the treatment of vascular-related diseases through functional revascularization is one of the most important research areas in tissue engineering. The aim of this study was to investigate the in vitro differentiation of umbilical CL-MSC into endothelial lineage cells. Methods: In this study, isolated cells were characterized for expression of MSC-specific marke...
متن کاملNeural Differentiation of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells
Background: Cell therapy is a potential therapeutic approach for neurodegenerative disorders. Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) are an appropriate source of stem cells for use in various cell-based therapies. Objectives: In this study, we examined a real-time PCR approach for neural differentiation of hUCB-MSCs in vitro. Materials and Methods: MSCs were cultu...
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Background & Objective: Diabetes is a major chronic metabolic disease in the world. Islet transplantation is a way to treat diabetes. Unfortunately, this method is restricted due to graft rejection and lack of donor islets. Mesenchymal Stem Cells (MSCS) have the ability to differentiate into Insulin-Producing Cells (IPCs). In this study, Human Umbilical Mesenchymal Stem Cells (HUMSCS) were in...
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ژورنال
عنوان ژورنال: Avicenna Journal of Medical Biochemistry
سال: 2016
ISSN: 2345-4113
DOI: 10.17795/ajmb-29066