Network pharmacology integrated molecular docking demonstrates the therapeutic mode of Panax ginseng against ovarian cancer

نویسندگان

چکیده

Purpose: To investigate the mode of action active ingredients Panax ginseng against ovarian cancer protein targets elucidated using a network pharmacology approach and molecular docking study. Methods: An integrated protein-protein interactions (PPI) targeting P. was constructed carried out for constituents target ginseng. Results: Ninety-six compounds were used simulation five different proteins from PPI linked to cancer. The protein-ligand interaction showed strong at site (p < 0.05).Conclusion: Ginsenosides their derivatives present in successfully inhibit several key enzymes associated with cancer, which may act as potential therapeutic disease.

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2023

ISSN: ['1596-5996', '1596-9827']

DOI: https://doi.org/10.4314/tjpr.v22i3.16