Nerve Growth Factor-Regulated Emergence of Functional -Opioid Receptors
نویسندگان
چکیده
منابع مشابه
Nerve growth factor-regulated emergence of functional delta-opioid receptors.
Sorting of intracellular G-protein-coupled receptors (GPCRs) either to lysosomes for degradation or to plasma membrane for surface insertion and functional expression is a key process regulating signaling strength of GPCRs across the plasma membrane in adult mammalian cells. However, little is known about the molecular mechanisms governing the dynamic process of receptor sorting to the plasma m...
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The factors regulating the differentiation of the endocrine cells of the pancreas are still unknown. In previous studies, we have demonstrated that, like neurones, various beta-cell lines express functional neurotrophin receptors. Moreover, Trk-A, the nerve growth factor (NGF) high-affinity receptor, is expressed in vivo in mature rat islets and early during development in the pancreatic ductal...
متن کاملEffects of Nerve Growth Factor, Insulin- Like Growth Factor-I and Collagen Gel on Peripheral Nerve Channel: Sensory, Functional and Regeneration Through Piezoelectric Electrophysiologicalal Study
Purpose: The limited availability of donor sites for nerve grafts continues to stimulate research toward finding suitable alternatives. Material and Methods: In the following study, the effects of direct administration of Nerve Growth Factor (NGF), Insulin - Like Growth Factor - I (IGF-I) , or / and collagen gel into Polyvinylidene Fluride (PVDF) gap was tested in a rat sciatic nerve model. A ...
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BACKGROUND/AIM Nerve growth factor (NGF) promotes the survival and differentiation of sensory and sympathetic neurons. Several studies have found that certain neuropathological factors stimulate NGF receptor expression and release the truncated nerve growth factor receptor (TNGFR) to biological fluids. The aim of this pilot study was to determine urine TNGFR levels in patients with dementia and...
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Ovarian cancer is the leading cause of death from gynecological malignancies. Understanding the biology of these tumors, as well as treatment modalities, has been challenging. The opioid growth factor (OGF; [Met(5)]-enkephalin) and the OGF receptor (OGFr) form an endogenous growth-regulating pathway in homeostasis and neoplasia. In this investigation, we examined the relationship of the OGF-OGF...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2010
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5296-09.2010