NERO: a pilot study but important step towards comprehensive management of obesity hypoventilation syndrome

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The obesity hypoventilation syndrome.

We only need to look around us to see that we are in an epidemic of obesity and obesity-related medical problems. The obesity hypoventilation syndrome is a disorder in which an obese person with normal lungs chronically hypoventilates. Obesity impairs ventilatory mechanics, increases the work of breathing and carbon dioxide production, results in respiratory muscle dysfunction, and reduces vent...

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Obesity hypoventilation syndrome.

The term obesity hypoventilation syndrome (OHS) refers to the combination of obesity and chronic hypercapnia that cannot be directly attributed to underlying cardiorespiratory disease. Despite a plethora of potential pathophysiological mechanisms for gas exchange and respiratory control abnormalities that have been described in the obese, the etiology of hypercapnia in OHS has been only partial...

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Defining obesity hypoventilation syndrome.

The definition of obesity hypoventilation syndrome (OHS) proposed by Hart et al raises two questions that we have tried to answer briefly in this letter. First, previous definitions of OHS included obstructive sleep apnoea (OSA); Hart et al have excluded it. Why? OSA is present in most patients with OHS and is partly responsible for the hypercapnia. We believe that it is useful to include it in...

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Grading obesity hypoventilation syndrome severity.

Obesity hypoventilation syndrome (OHS) is commonly defined as a combination of obesity (body mass index (BMI) .30 kg?m), waking arterial hypercapnia (arterial carbon dioxide tension (Pa,CO2) .6.0 kPa (45 mmHg)) and sleepdisordered breathing. Essential to the diagnosis is exclusion of other causes of alveolar hypoventilation [1]. The lack of a standardised definition of OHS in general, and of OH...

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ژورنال

عنوان ژورنال: Thorax

سال: 2017

ISSN: 0040-6376,1468-3296

DOI: 10.1136/thoraxjnl-2017-211032