منابع مشابه
role of vascular endothelial growth factors in ocular neovascular diseases
the most important progress in the field of retinal diseases during recent years might be the introduction of pharmacotherapy. age-related macular degeneration for instance was an irreversible disease leading to permanent anatomical and functional changes in the macula up to the previous decade; however, the use of anti-vascular endothelial growth factor agents (anti-vegfs) not only stops the p...
متن کاملVascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders
The introduction of pharmacotherapy has been one of the most important advances in the management of retinal disorders. Age-related macular degeneration (AMD) was once considered as an irrepressible disease leading to permanent macular damage, however anti-vascular endothelial growth factor (anti-VEGF) agents are now believed to halt the progression of the condition and improve vision in a cons...
متن کاملIntravitreal growth factors in proliferative diabetic retinopathy: correlation with neovascular activity and glycaemic management.
AIM Many growth factors are implicated in proliferative diabetic retinopathy (PDR). It was decided to test the hypothesis that no one factor is predominant but that a regular profile of levels of different growth factors might be operating, and that the profile might differ according to whether or not insulin therapy was part of the patient's glycaemic management. The levels of several growth f...
متن کاملSwitching Anti-Vascular Endothelial Growth Factors in Refractory Neovascular Age-Related Macular Degeneration.
BACKGROUND AND OBJECTIVE Anti-vascular endothelial growth factor (VEGF) therapy is the treatment of choice for cases with neovascular age-related macular degeneration (AMD). Switching to an alternate anti-VEGF has been suggested as a possible option for resistant cases. The purpose of this review is to evaluate whether the timing of switching affects treatment outcomes. PATIENTS AND METHODS A...
متن کاملNongenetic risk factors for neovascular age-related macular degeneration.
PURPOSE To create a risk model for neovascular age-related macular degeneration (nAMD) based on nongenetic factors. METHODS In this case-control study, 1459 individuals were included, 445 patients showed nAMD and 1014 were healthy controls. Participants were randomly assigned into a training set (containing two-thirds of individuals) and a validation set. Stepwise logistic regression analysis...
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ژورنال
عنوان ژورنال: Eye
سال: 1991
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1991.31