Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline
نویسندگان
چکیده
منابع مشابه
Thrombocytopenia and platelet transfusion
Thrombocytopenia is caused by disorders impairing platelet production, causing platelet destruction or leading to platelet sequestration. In addition, there are both congenital and acquired disorders of platelet function. These latter conditions may lead to the functional equivalent of thrombocytopenia, often despite the presence of a normal platelet count. Platelet transfusion represents an im...
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Five percent of newborn infants admitted to UK neonatal units during a recent study developed a platelet count <60 × 10(9)/l, and 60% of these were transfused platelets. This review summarises the common causes and mechanisms of thrombocytopenia in the newborn. Relevant evidence relating the platelet count to the risk of haemorrhage is reviewed, and current UK guidance on transfusion thresholds...
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Neonatal alloimmune thrombocytopenia (NAIT) is a fetomaternal incompatibility most commonly induced by maternal anti-HPA-1a, IgG alloantibodies against a polymorphic epitope of the glycoprotein IIb/IIIa complex in approximately 97.5% of white patients. Current guidelines recommend transfusion of immunologically compatible platelets to prevent cerebral hemorrhage, the most severe complication in...
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Background: Infant jaundice is one the most common causes of hospitalization in infant in the first month of birth, which is defined an abnormal increase in blood bilirubin levels. Exchange transfusion is the recommended treatment for neonatal jaundice who do not respond to phototherapy and experience dangerous complication of jaundice and signs of kernicterus. However, this treatment may lead ...
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Abstract Objective: To assess the incidence of thrombocytopenia and changes in various platelet parameters, in culture positive neonatal sepsis. Methods: This was prospective study conducted over a period of one year from December 2009 to November 2010 in neonatal intensive care unit of DDUH Hospital, a tertiary care hospital in Delhi, North India. All babies who were admitted during this perio...
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ژورنال
عنوان ژورنال: Clinical Pediatric Hematology-Oncology
سال: 2019
ISSN: 2233-5250,2233-4580
DOI: 10.15264/cpho.2019.26.2.67