Neonatal Subventricular Zone Electroporation

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Neonatal subventricular zone electroporation.

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Much excitement has been generated by the identification of adult brain regions harboring neural stem cells and their continual generation of new neurons throughout life. This is an important departure from traditional views of the germinal potential of the postnatal brain. However, a more profound paradigm shift may be emerging. Studies of adult neurogenesis in the subventricular zone (SVZ) ha...

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Neonatal pial surface electroporation.

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Altered fate of subventricular zone progenitor cells and reduced neurogenesis following neonatal stroke.

OBJECTIVE To investigate the effects of neonatal stroke on progenitor cells lining the lateral ventricles. METHODS Intraventricular injection of replication-incompetent green fluorescent protein (GFP)-expressing lentivirus was performed in postnatal day 1 (P1) rats to specifically label radial glia/type B neural stem cells and ependymal cells of the lateral ventricle. A subset of animals was ...

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Erythropoietin Attenuates Brain Injury, Subventricular Zone Expansion, and Sensorimotor Deficits in Hypoxic-Ischemic Neonatal Rats

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ژورنال

عنوان ژورنال: Journal of Visualized Experiments

سال: 2013

ISSN: 1940-087X

DOI: 10.3791/50197