Neonatal purpura fulminans due to protein C deficiency

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Management of neonatal purpura fulminans with severe protein C deficiency.

Neonatal purpura fulminans is a life threatening clinical entity characterized by extensive subcutaneous thrombosis and disseminated intravascular coagulation usually manifesting shortly after birth. We report an autosomal recessive form of the disease in a neonate who was diagnosed with compound heterozygosity for mutations in his protein C gene as the molecular basis of his disorder.

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Neonatal Purpura Fulminans

Neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. It manifests as DIC and extensive subcutaneous thrombosis. The condition is often fatal unless there is prompt diagnosis, and judicious therapy. The most important causes of this condition are infections and congenital deficiency of anticoagulant proteins C and S.In the case of PC (p...

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neonatal purpura fulminans

neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. it manifests as dic and extensive subcutaneous thrombosis. the condition is often fatal unless there is prompt diagnosis, and judicious therapy. the most important causes of this condition are infections and congenital deficiency of anticoagulant proteins c and s.in the case of pc (p...

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ژورنال

عنوان ژورنال: Ceylon Medical Journal

سال: 2015

ISSN: 2386-1274,0009-0875

DOI: 10.4038/cmj.v45i3.8116