Neonatal cholestasis and hypopituitarism.

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Neonatal cholestasis and hypopituitarism 787 Neonatal cholestasis and hypopituitarism

Optic nerve hypoplasia with hypopituitarism and intact septum pellucidum is a variant of septo-optic dysplasia or deMorsier's syndrome.' Although neonatal jaundice has been seen with this syndrome, the association with severe prolonged cholestatic jaundice has not been emphasised. We describe three patients who presented with cholestatic jaundice and were found to have optic nerve hypoplasia an...

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Neonatal cholestasis and hypopituitarism.

We read with interest the paper by Kaufman et al' on neonatal cholestasis and hypopituitarism. We have been treating a similar patient whose problems were complicated by diabetes insipidus of pituitary origin. She was referred from another hospital at the age of 1 month for assessment of secondary hypothyroidism, cholestatic jaundice, temperature instability, and microcephaly. She was born at 4...

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Neonatal cholestasis and hypopituitarism 787

Optic nerve hypoplasia with hypopituitarism and intact septum pellucidum is a variant of septo-optic dysplasia or deMorsier's syndrome.' Although neonatal jaundice has been seen with this syndrome, the association with severe prolonged cholestatic jaundice has not been emphasised. We describe three patients who presented with cholestatic jaundice and were found to have optic nerve hypoplasia an...

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Evaluation of an Infant with Cholestasis and Congenital Hypopituitarism

We are reporting an infant with persistent abnormal liver function, neonatal jaundice, and intermittent hypoglycemia. Evaluation confirmed congenital hypopituitarism, in the absence of congenital anomalies and midline defect. His jaundice and abnormal liver function improved after treatment with Levothyroxine and hydrocortisone.

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Neonatal Hypopituitarism: Unusual Presentation

Congenital hypopituitarism is a rare condition associated with possible serious complications and long-term neurological sequelae, if not promptly recognized and treated.1 Neonates with congenital hypopituitarism may present with or without associated developmental defects, such as ocular, midline, and genital abnormalities. They may also present with nonspecific symptoms, including hypoglycemi...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1984

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.59.8.787