Neonatal cerebral sinovenous thrombosis: two cases, two different gene polymorphisms and risk factors

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چکیده

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Cerebral Sinovenous Thrombosis

Cerebral sinovenous thrombosis (CSVT) is a rare but serious cerebrovascular disorder affecting children from the newborn period through childhood and adolescence. The incidence is estimated at 0.6/100,000/year, with 30-50% occurring in newborns. Causes are diverse and are highly age dependent. Acute systemic illness is the dominant risk factor among newborns. In childhood CSVT, acute infections...

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Neonatal cerebral sinovenous thrombosis from symptom to outcome.

BACKGROUND AND PURPOSE Cerebral sinovenous thrombosis is a rare disease with severe neurological sequelae. The aim of this retrospective multicenter study was to investigate the clinical course, possible risk factors, and outcome of a cohort of neonatal patients with sinovenous thrombosis and, second, to estimate the incidence in The Netherlands. METHODS From January 1999 to March 2009, a rev...

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Investigators from Erasmus University Hospital in Belgium and Gustave-Dron Hospital and Roger-Salengro Hospital in France studied the clinical and neuroradiologic characteristics of cerebral sinovenous thrombosis (CSVT) in neonates and children.

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A boy (age: 71/12 years) with acute lymphoblastic leukaemia developed thrombosis of the sinus sagitalis superior with secondary haemorrhagic infarction while on induction treatment with vincristine, prednisone, and asparaginase. Based on this report, the potential pathogenic mechanisms are discussed with respect to congenital prothrombotic defects as well as to the role of antileukaemic treatme...

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cerebral sinovenous thrombosis (csvt) in a neonate with different manifestations

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ژورنال

عنوان ژورنال: The Turkish Journal of Pediatrics

سال: 2017

ISSN: 0041-4301

DOI: 10.24953/turkjped.2017.01.012