Neonatal bone marrow transplantation for severe combined immunodeficiency
نویسندگان
چکیده
منابع مشابه
Neonatal bone marrow transplantation for severe combined immunodeficiency.
AIMS To evaluate outcome following neonatal bone marrow transplantation (BMT) for severe combined immunodeficiency (SCID) when there is a family history of a previously affected sibling, and to compare results with those published for in utero BMT. METHODS A retrospective review of cases referred and transplanted between 1987 and 1999, focusing on infectious and graft versus host disease (GvH...
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Severe combined immunodeficiency (SCID) is fatal in early childhood if unrecognized and if not treated. The aim was to determine the efficacy of T cell depleted bone marrow transplantation (TCD BMT) in the treatment of children with SCID. Eleven children diagnosed with SCID received histocompatible related donor bone marrow transplantation--HRD BMT (group I). Thirty seven children diagnosed wit...
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Bone marrow transplantation in human X-linked severe Normal percentages of T cells and T-cell mitogenic recombined immunodeficiency (XSCID) without pretransplant sponses were attained by 3 months posttransplant. CD3 T conditioning results in engraftment of donor T cells and recells after transplantation expressed the CD45RA isoform constitution of T-cell function but engraftment of few, if any,...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition
سال: 2001
ISSN: 1359-2998,1468-2052
DOI: 10.1136/fn.85.2.f110