Neogenin Interacts with Hemojuvelin through Its Two Membrane-Proximal Fibronectin Type III Domains
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چکیده
منابع مشابه
Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains.
Hemojuvelin is a recently identified iron-regulatory protein that plays an important role in affecting the expression of hepcidin, a key iron regulatory hormone. Although the underlying mechanism of this process is not clear, several hemojuvelin-binding proteins, including the cell surface receptor neogenin and bone morphogenetic protein (BMP) cytokines, have been identified. The ectodomain of ...
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ژورنال
عنوان ژورنال: Biochemistry
سال: 2008
ISSN: 0006-2960,1520-4995
DOI: 10.1021/bi800036h