Neither the patient nor the physician could see anything: Atypical Bing-Neel syndrome

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Bing and Neel Syndrome

Introduction. We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis. Case Report. a 57-year-old man was followed up since October 2003 for a typical Waldenström's macroglobulinemia. A first complete remission was obtained with chlorambucil. In August 2004, he relapsed. A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, an...

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A Bing-Neel syndrome case

Bing-Neel syndrome (BNS) is an extremely rare neurologic complication of WM. Herein, we aimed to report a BNS case. A 57 years old women admitted to hospital with fever, weight loss and cough in November 2009. Complete blood count was resulted as hemoglobin 7.4 gr/dl, white blood cell 1.8 × 103/μl, thrombocyte 216 × 103/ μl. Kidney and liver function tests were in normal range. Anemia parameter...

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Bing-Neel syndrome: a rare complication of Waldenström macroglobulinemia.

A 61-year-old woman with Waldenström macroglobulinemia (WM) was treated with 6 cycles of cyclophosphamide, rituximab, and dexamethasone between December 2011 and May 2012, and she achieved complete remission. She was given maintenance rituximab once every 3 months. Eighteen months later, the patient presented with complaints of headache and blurry vision. Physical examination revealed aphasia, ...

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Therapeutic Experience of Bing-Neel Syndrome Associated with Waldenstrom's Macroglobulinemia

Waldenstrom's macroglobulinemia is an uncommon low-grade B-cell lymphoproliferative disorder in which monoclonal immunoglobulin M is produced. Neurological symptoms due to hyperviscosity are frequent manifestations of Waldenstrom's macroglobulinemia. However, central nervous system infiltration by plasmacytoid lymphocytes (Bing-Neel syndrome) has only rarely been reported. We report a case of a...

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Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome.

Bing Neel syndrome is a rare disease manifestation of Waldenström's macroglobulinemia that results from infiltration of the central nervous system by malignant lymphoplasmacytic cells. In this guideline we describe the clinical symptoms, as well as the appropriate laboratory and radiological studies, that can aid in the diagnosis. The presentation of Bing Neel syndrome may be very diverse, and ...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 2016

ISSN: 0361-8609

DOI: 10.1002/ajh.24411