Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate
نویسندگان
چکیده
منابع مشابه
TBCK Influences Cell Proliferation, Cell Size and mTOR Signaling Pathway
Mammalian target of rapamycin (mTOR) is a central regulator for both cell proliferation and cell growth; however, little is known about the regulation of mTOR expression at the transcriptional level. Here, we provide evidences that a conserved human protein TBCK (TBC1 domain containing kinase) is involved in the regulation of mTOR signaling pathway. Depletion of TBCK significantly inhibits cell...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2019
ISSN: 1662-453X
DOI: 10.3389/fnins.2019.01022