NEAT1 promotes retinoblastoma progression via modulating miR‐124
نویسندگان
چکیده
منابع مشابه
Retinoblastoma Progression
The Vision Center, Division of Pediatric Ophthalmology, Department of Surgery, and The Saban Research Institute, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, United States USC Eye Institute, Department of Ophthalmology, and Norris Comprehensive Cancer Center, Keck School ofMedicine of the University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033,...
متن کاملLong noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-κB pathway
Nasopharyngeal carcinoma (NPC) is one of the most common malignancies and seriously endangers people's health. Recently, long noncoding RNA (lncRNA) NEAT1 has been determined as an oncogenic gene in a variety of cancers. However, the effect of NEAT1 in NPC and its underlying mechanism have not been well elaborated. In this study, the data showed that NEAT1 was upregulated and miR-124 was downre...
متن کاملThe FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.
The pathophysiological function of the forkhead transcription factor FOXN3 remains to be explored. Here we report that FOXN3 is a transcriptional repressor that is physically associated with the SIN3A repressor complex in estrogen receptor-positive (ER+) cells. RNA immunoprecipitation-coupled high-throughput sequencing identified that NEAT1, an estrogen-inducible long noncoding RNA, is required...
متن کاملlncRNA NEAT1 is closely related with progression of breast cancer via promoting proliferation and EMT.
OBJECTIVE Breast cancer (BC) is one of the most common cancers in females. Abnormal proliferation and metastasis are key reasons that cause mortality in BC patients. More and more evidence showed that lncRNA played an important role in the BC development, but the mechanism was not well established. PATIENTS AND METHODS The expression of lncRNA NEAT1 was detected in 40 BC patients by qRT-PCR t...
متن کاملLong non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway
Recently, the long non-coding RNA (lncRNA) NEAT1 has been identified as an oncogenic gene in multiple cancer types and elevated expression of NEAT1 was tightly linked to tumorigenesis and cancer progression. However, the molecular basis for this observation has not been characterized in progression of non-small cell lung cancer (NSCLC). In our studies, we identified NEAT1 was highly expressed i...
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ژورنال
عنوان ژورنال: Journal of Cellular Biochemistry
سال: 2019
ISSN: 0730-2312,1097-4644
DOI: 10.1002/jcb.28825