Nearing 125 Years of ASEE

Ribosome Rescue, Nearing the End

In eukaryotes, Dom34 is involved in the rescue of ribosomes that stall on mRNAs during protein synthesis. Using ribosome profiling, Guydosh and Green reveal that, in addition to rescue of ribosomes stalled on truncated mRNAs, Dom34 also recycles ribosomes that are unexpectedly found in the 3' untranslated regions of many cellular mRNAs.

Rabies, Still Neglected after 125 Years of Vaccination

Rabies is a viral zoonotic infection of the central nervous system caused by a lyssavirus. The disease is fatal without proper post exposure prophylaxis (PEP). In July 1885, Louis Pasteur obtained his first success against rabies by vaccinating Joseph Meister, a 9-year-old boy presenting with multiple deep bite wounds [1]. After more than 700 successful inoculations, Pasteur launched an interna...

125 Years of Radiative Transfer: Enduring Triumphs and Persisting Misconceptions

The evolution of phenomenological and microphysical approaches to radiative transfer (RT) and directional radiometry (DR) is outlined. The importance of the seminal 1887 paper by Eugen von Lommel is discussed. It is shown that owing to recent advances, the disciplines of RT and DR have finally become legitimate branches of statistical electromagnetics.

Diversity and change in suicide seasonality over 125 years.

BACKGROUND Recent research has corroborated the notion that seasonality in suicide is more heterogeneous and less consistent than postulated by former scholars. This work investigates the smoothing out of suicide seasonality in Switzerland between the late 19th and the end of the 20th century. It includes analyses by region and by suicide method. METHODS Monthly suicide frequencies in Switzer...

Continuous deep sedation in patients nearing death.