NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients
نویسندگان
چکیده
منابع مشابه
Severe malaria in immigrant haematological patient
Severe malaria is a life-threatening condition caused by Plasmodium falciparum. Rupture of red blood cells when merozoites release to the bloodstream is responsible for the clinical manifestations, febrile fever reaching 39 °C, and other unspecific symptoms. P. falciparum is considered as the worst form of malaria. Moreover, this species has cytoadherence to red blood cells. This can lead to an...
متن کاملPolymorphism analysis of malaria susceptibility biomarkers in G6PD deficiency patients
Abstract Background: Several studies suggested that some traits and polymorphisms in human genome such as G6PD deficiency and other genes have protective effects on susceptibility to malaria infection . Methods: In present study we investigated the prevalence of TNF [1] -244GgA, TNF [1] - 308 GgA,TNF [1] -238GgA, NOS2-954GgC, MBL54GgA, MBL 57GgA, MBL IVSI - 5 GgA polymorphisms and G6P...
متن کاملHaematological Parameters in open angle Glaucoma Patients
There is potential for blood related factors to affect aqueous production or optic nerve functions. There have been relationships between inflammatory cell count and glaucoma. Eosinophils have inverse relationship with steroids which is used to induce ocular hypertension. Here we compare hematological parameters for a group of 68 chronic openangle glaucoma (OAG) patients and a non-glaucomatous ...
متن کاملAssociation analyses of NCR3 polymorphisms with P. falciparum mild malaria.
Plasmodium falciparum malaria is a major cause of morbidity and mortality in many developing countries especially in sub-Saharan Africa. A susceptibility locus for mild malaria has been mapped to the MHC region, and TNF polymorphisms have been associated with mild malaria. The Natural Cytotoxicity-triggering Receptor 3 (NCR3) gene is located in the peak region of linkage, and is 15kb distal to ...
متن کاملPlatelet distribution width, mean platelet volume and haematological parameters in patients with uncomplicated plasmodium falciparum and P. vivax malaria
BACKGROUND The association between the haematological profile (including abnormal platelets) and malaria is not completely understood. There are few published data on haematological profiles of malaria patients in areas with unstable malaria transmission. The current study was conducted to investigate if the haematological parameters, including platelet indices, were reliable predictors for mi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PeerJ
سال: 2018
ISSN: 2167-8359
DOI: 10.7717/peerj.6048