Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats
نویسندگان
چکیده
منابع مشابه
Effect of aqueous ethanol extract of Hypericum perforatum on naloxane-precipitated opium withdrawal syndrom
The aqueous-ethanol extract of the Hypericum perforatum (Hp-Ext.) was studied for its possible effect on Naloxone (NLX)-precipitated Opium withdrawal physical signs in rats. Purified Opium was used to induce dependence in rats using 8 days treatment schedule. The animals received Opium extract orally twice daily at 09:00 hrs and 19:00 hrs starting with initial dose of 80 mg/kg (equivalent to 8 ...
متن کاملEffect of aqueous ethanol extract of Hypericum perforatum on naloxane-precipitated opium withdrawal syndrom
The aqueous-ethanol extract of the Hypericum perforatum (Hp-Ext.) was studied for its possible effect on Naloxone (NLX)-precipitated Opium withdrawal physical signs in rats. Purified Opium was used to induce dependence in rats using 8 days treatment schedule. The animals received Opium extract orally twice daily at 09:00 hrs and 19:00 hrs starting with initial dose of 80 mg/kg (equivalent to 8 ...
متن کاملThe effect of gabapentin on the withdrawal signs in morphine-dependent male rats
Acute morphine withdrawal is considered to be the physical manifestation of dependence, emerging when morphine administration is stopped or after the administration of an opiate antagonist, such as naloxone. Gabapentin, which is an antiepileptic, agent, enhances the analgesic effect of morphine in healthy volunteers, but its effect on morphine dependence and withdrawal signs has not determined ...
متن کاملTransgenic Hypericum perforatum.
Plant transformation is an important tool with many applications in modern plant biology. Although this technique is primarily used to produce superior crop varieties, it is also being utilized to answer basic questions concerning gene function and regulation in contemporary functional genomics research. In our laboratory, we have established a transformation system for Hypericum perforatum. Th...
متن کاملThe effect of gabapentin on the withdrawal signs in morphine-dependent male rats
Acute morphine withdrawal is considered to be the physical manifestation of dependence, emerging when morphine administration is stopped or after the administration of an opiate antagonist, such as naloxone. Gabapentin, which is an antiepileptic, agent, enhances the analgesic effect of morphine in healthy volunteers, but its effect on morphine dependence and withdrawal signs has not determined ...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2013
ISSN: 1388-0209,1744-5116
DOI: 10.3109/13880209.2013.854811