Natural oscillation frequencies in the two lateral prefrontal cortices induced by Transcranial Magnetic Stimulation

Abstract Different cortical regions respond with distinct rhythmic patterns of neural oscillations to Transcranial Magnetic Stimulation (TMS). We investigated natural frequencies induced by TMS in left and right homologous dorsolateral prefrontal cortices (DLPFC) related hemispheric differences. In 12 healthy young adults, single-pulse was delivered different blocks close F3 F4 channels target DLPFC. An occipital site near PO3 stimulated as control. TMS-related spectral perturbation analyses were performed on recorded EEG data. A widespread unspecific increase theta power observed for all stimulation sites. However, greater alpha activity a 10.58 Hz frequency, while over the DLPFC resulted similar beta band modulations frequency 18.77 18.5 Hz, respectively. particular, specific stronger than The is more specifically tuned its when it directly counterpart (or posterior region), increases similarly irrespective whether or through stimulation. These results yield important implications both basic neuroscience research inter-hemispheric interactions clinical applications.