Natural killer cells, miscarriage, and infertility
نویسندگان
چکیده
منابع مشابه
Natural killer cells in female infertility and recurrent miscarriage: a systematic review and meta-analysis.
INTRODUCTION Embryo implantation is a complex process involving maternal hormonal changes, immune responses and maturational events in the embryo. A pregnancy could fail when these events are not synchronized. It is speculated that in women, an elevation of natural killer (NK) cells may have an effect on reproductive performance, and NK cell levels in blood are currently being used as a diagnos...
متن کاملThe State of Peripheral Blood Natural Killer Cells and Cytotoxicity in Women with Recurrent Pregnancy Loss and Unexplained Infertility
Objective : The prognostic value of peripheral natural killer (pNK) cells, as a screening test in women with recurrent pregnancy loss (RPL) and unexplained infertility is still a matter for discussion. The aim of this study was to compare the percentage of circulating CD56+NK cells, CD69 and perforin markers between women with unexplained infertility and RPL with healthy control group. Material...
متن کاملIncreased Natural Killer Cells Activity in Schizophrenic Patients
Background: Schizophrenia has been associated with altered immunity. Different studies regarding natural killer cell activity (NKA) in schizophrenic patients have shown inconsistent results. Objectives: To evaluate NK cell activity in schizophrenic patients in comparison with healthy control individuals. Methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...
متن کاملDetailed analysis of peripheral blood natural killer (NK) cells in women with recurrent miscarriage.
BACKGROUND Increased peripheral blood natural killer (NK) cell activity has been associated with unexplained reproductive failure including recurrent (three or more) miscarriages (RM). Studies have reported abnormalities in both numbers (absolute and proportion) and activation. This study assessed numerous NK cell parameters to determine which (if any) are altered in women with RM compared with...
متن کاملNatural killer cells
What do they do? NK cells are equipped with cytotoxic granules that contain the arsenal of cytotoxic molecules used in killing virally infected and cancerous cells. They recognize their targets, in part, by means of activating signals that are only just beginning to be identified, but also by detecting cells that are deficient in cell-surface class I molecules of the major histocompatibility co...
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ژورنال
عنوان ژورنال: BMJ
سال: 2004
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.329.7477.1283