Natural history of chronic Chagas' heart disease: prognosis factors

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Natural history of chronic Chagas' heart disease: prognosis factors.

Chronic Chagas' disease shows several progression modes. Usually, the different clinical syndromes manifest themselves together, however, isolated forms can occur. Cardiac arrhythmias, which are very frequent, are present in about 50% of patients. The cardiac damage manifests itself later, with the emergence of heart failure. Thromboembolism can occur in both pulmonary and systemic circulation....

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Pathogenesis of chronic Chagas heart disease.

BACKGROUND Chagas disease remains a significant public health issue and a major cause of morbidity and mortality in Latin America. Despite nearly 1 century of research, the pathogenesis of chronic Chagas cardiomyopathy is incompletely understood, the most intriguing challenge of which is the complex host-parasite interaction. METHODS AND RESULTS A systematic review of the literature found in ...

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Thromboembolism in chronic Chagas' heart disease.

Thromboembolic episodes are particularly important in chronic Chagas' heart disease. Systemic and pulmonary embolic phenomena are important complications of the disease. Prophylaxis of the thromboembolic phenomena with anticoagulant therapy should be considered in several clinical forms of the disease. Further studies will have to address the stratification risk issue.

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Electrophysiologic study in chronic Chagas' heart disease.

Cardiac arrhythmias are common in chagasic patients. Electrophysiologic study is an invasive procedure for the investigation of sinus node function, atrioventricular node conduction and intraventricular (His-Purkinje) conduction and the mechanism of tachycardias. It is useful in elucidating syncope, dizziness and tachycardiac palpitations that remain unexplained by non-invasive diagnostic metho...

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Value of echocardiography for diagnosis and prognosis of chronic Chagas disease cardiomyopathy without heart failure.

OBJECTIVES To establish the usefulness of echocardiography for the clinical classification of patients with Chagas disease and to determine the predictors of mortality and clinical events. METHODS 849 patients with chronic Chagas disease with a mean follow up of 9.9 years were studied. On admission, ECG, chest radiograph, and two dimensional echocardiogram were obtained from all patients. Cli...

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ژورنال

عنوان ژورنال: Sao Paulo Medical Journal

سال: 1995

ISSN: 1516-3180

DOI: 10.1590/s1516-31801995000200009