منابع مشابه
Prospects of boswellic acids as potential pharmaceutics.
Boswellic acids have long been considered the main bioactive components of frankincense, and many studies in vitro and in animals as well as several clinical studies have confirmed their various bioactivities. In particular, a large number of mechanistic studies have confirmed their anti-inflammatory and antitumor activities. However, not every boswellic acid exhibits a satisfactory pharmacolog...
متن کاملMetabolism of boswellic acids in vitro and in vivo.
Boswellia serrata resin dry extract is among the few herbal remedies designated with an orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (BAs), the main active ingredients of B. serrata extracts, have potent anti-inflammatory properties, and may represent promising agents for the treatment of inflammatory diseases. Pharmacokinetic studies, however, r...
متن کاملInhibition by boswellic acids of human leukocyte elastase.
Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene biosynthesis and exert potent anti-inflammatory effects. Screening for additional effects of boswellic acids on further proinflammatory pathways, we observed that acetyl-11-keto-beta-boswellic acid, an established direct, nonredox and noncompetitive 5-lipoxygenase inhibitor,...
متن کاملInstitute for Soldier Nanotechnologies
A three-member team designed to leverage the unique capabilities of the US Army, industry, and MIT, the ISN mission is to provide a dramatic increase in survivability to the individual Soldier through nanoengineered materials and devices incorporated within a lighter-weight uniform. This mission includes not only decreasing the weight that Soldiers carry, but also improving blast and ballistic ...
متن کاملA cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis
BACKGROUND Boswellic acids (BAs) show anti-inflammatory properties in a variety of inflammatory diseases, including rheumatoid arthritis, osteoarthritis, and asthma. A topical administration route is currently used to deliver active compounds in psoriatic and eczematous patients. In this double-blind study we compare a novel BA formulation (containing Bosexil(®), INCI [International Nomenclatur...
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ژورنال
عنوان ژورنال: American Journal of Drug Discovery and Development
سال: 2013
ISSN: 2150-427X
DOI: 10.3923/ajdd.2014.1.11