Nanoparticulate Transscleral Ocular Drug Delivery
نویسندگان
چکیده
منابع مشابه
Nanoparticulate Drug Delivery System of Cyclosporine
Recent research on idealizing drug delivery systems which is progressing at a prodigious rate, aims at the development of drug delivery systems with maximum therapeutic benefits of drug delivery thus resulting in safe and effective management of diseases. In the present study Nanoparticlulate drug delivery system for Cyclosporine was developed, that would overcome the therapeutic risks of conve...
متن کاملOcular Drug Delivery
Traditionally, medication is delivered to the eye by three main mechanisms: Topical ocular administration, systemic administration, and intraocular or periocular injection. Each of these methods has significant disadvantages. Topical ocular solutions or ointments have less than a 1% penetration, have rapid dilution and tear washout, and rely substantially on owner compliance to administer the m...
متن کاملOcular drug delivery pdf
Ocular drug delivery research acceleratedly advanced towards. Ocular drug delivery necessitates and helps drug delivery scientists to. Urgent need to develop ocular drug delivery systems which provide controlled. Pdflucentis-prescribing.pdf accessed on 18 October 2010. Delivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular rou...
متن کاملEffect of eye pigmentation on transscleral drug delivery.
PURPOSE To determine the influence of eye pigmentation on transscleral retinal delivery of celecoxib. METHODS Melanin content in ocular tissues of both the strains was determined by sodium hydroxide solubilization METHOD The affinity of celecoxib to synthetic and natural melanin was estimated by co-incubating celecoxib and melanin in isotonic phosphate-buffered saline. The binding affinity ...
متن کاملEffect of benzalkonium chloride on transscleral drug delivery.
PURPOSE To investigate the effect and safety of benzalkonium chloride on transscleral drug delivery in the rabbit after continuous intrascleral administration. METHODS Betamethasone 21-phosphate (BP) aqueous solutions, with or without benzalkonium chloride (BAK), were continuously administered to albino rabbit sclera with an osmotic pump for 1 week. The BP concentrations in the aqueous humor,...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Research & Therapeutics
سال: 2014
ISSN: 2167-7956
DOI: 10.4172/2167-7956.1000116