منابع مشابه
Autoimmune Inner Ear Disease- A Clinical Viewpoint
Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...
متن کاملCell- and gene-therapy approaches to inner ear repair.
Sensorineural hearing loss is the most common sensory disorder in humans. It is primarily due to the degeneration of highly specialised mechanosensory cells in the cochlea, the so-called hair cells. Hearing problems can also be caused or further aggravated by the death of auditory sensory neurons that convey the information from the hair cells to the brain stem. Despite the discovery of stem/pr...
متن کاملInvestigating a Cell Replacement Therapy in the Inner Ear
The mammalian auditory system is sensitive to genetic disorders, aging and injuries caused by overstimulation, ototoxic drugs and viral infections. Since the sensory epithelium (the organ of Corti) and the spiral ganglion neurons (SGNs) in adult mammalian do not regenerate spontaneously when they are damaged, a cell substitution strategy was proposed to compensate the function of the degenerate...
متن کاملWhen inner ear stem cell therapy becomes a reality.
Editorial The clinical treatment of hearing loss is at once sophisticated and crude. Surgeons can use microsurgical techniques and lasers to manipulate ossicular prostheses fractions of a millimeter with often astounding improvement in hearing, for example, in the case of stapes fixation due to otosclerosis. For profound sensorineural impairment, the cochlea may be surgically implanted with an ...
متن کاملInside the inner ear
There are dozens of different myosin isozymes, though it's not clear why cells require such a diversity. These images of fluorescently-labelled hair cells from the inner ears of frog, guinea pig and mouse show the localization of actin (red at top left and bottom right) and of four different forms of myosin (green, except at bottom left, where myosin VI is labelled in red). Hair cells are the r...
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ژورنال
عنوان ژورنال: World Journal of Otorhinolaryngology
سال: 2013
ISSN: 2218-6247
DOI: 10.5319/wjo.v3.i4.114