Nanoclay Suspension-Enabled Extrusion Bioprinting of Three-Dimensional Soft Structures

نویسندگان

چکیده

Abstract Three-dimensional (3D) extrusion printing of cellular/acellular structures with biocompatible materials has been widely investigated in recent years. However, the requirement a suitable solidification rate printable ink constrains utilization extrusion-based 3D techniques. In this study, nanoclay yield-stress suspension-enabled system and demonstrated to overcome constraints during printing. Utilizing liquid–solid transition property suspension, two fabrication approaches, including support bath-enabled nanoclay-enabled direct printing, have proposed. For former approach, (Laponite® EP) used as bath material fabricate alginate-based tympanic membrane patches. The constituents desired mechanical patches facilitate process. latter XLG) an internal scaffold help print poly (ethylene glycol) diacrylate (PEGDA)-based neural chambers, which can be further cross-linked air. Mechanical stress analysis performed explore geometric limitation Laponite® XLG-PEGDA chambers.

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ژورنال

عنوان ژورنال: Journal of Manufacturing Science and Engineering-transactions of The Asme

سال: 2021

ISSN: ['1087-1357', '1528-8935']

DOI: https://doi.org/10.1115/1.4051010