Nano cobalt-copper ferrite catalyzed regioselective α-C(sp3)–H cyanation of amines: Secondary, tertiary, and drug molecules
نویسندگان
چکیده
منابع مشابه
Gold-complexes catalyzed oxidative α-cyanation of tertiary amines.
Oxidative α-cyanation of tertiary amines is catalyzed by gold complexes with trimethylsilyl cyanide to afford the corresponding α-aminonitriles in the presence of tert-butyl hydroperoxide in good to excellent yields under acid-free conditions at room temperature.
متن کاملIron catalyzed oxidative cyanation of tertiary amines.
Iron(ii) and iron(iii) salts catalyze the oxidative alpha-cyanation of tertiary amines by trimethylsilyl cyanide in the presence of tert-butylhydroperoxide under acid-free conditions at room temperature.
متن کاملCopper-catalyzed regioselective ortho C-H cyanation of vinylarenes.
A copper-based catalytic technique for the regioselective ortho C-H cyanation of vinylarenes has been developed. This method provides an effective means for the selective functionalization of vinylarene derivatives. A copper-catalyzed cyanative dearomatization mechanism is proposed to account for the regiochemical course of this reaction.
متن کاملHydroamination of terminal alkynes with secondary amines catalyzed by copper: regioselective access to amines.
A simple and convenient copper-catalyzed hydroamination of arylacetylenes with secondary amines has been performed giving a simple access to aliphatic amines after reduction of the hydroaminated products (E-enamines). Here we described a mild catalytic system utilizing CuCN precatalyst without any additive ligands in a solvent-free system.
متن کاملN-Cyanation of Secondary Amines Using Trichloroacetonitrile.
A one-pot N-cyanation of secondary amines has been developed using trichloroacetonitrile as an inexpensive cyano source. A diverse range of cyclic and acyclic secondary amines can be readily transformed into the corresponding cyanamides in good isolated yields, with the method successfully utilized in the final synthetic step of a biologically active rolipram-derived cyanamide. This approach ex...
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ژورنال
عنوان ژورنال: Catalysis Communications
سال: 2021
ISSN: 1566-7367
DOI: 10.1016/j.catcom.2020.106211