Nalidixic Acid as a Decontaminant in Löwenstein-Jensen Medium
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Rifampicin stability in 7 H 9 broth and Löwenstein - Jensen medium 1
18 Objectives: To monitor the stability of rifampicin (RIF) in Löwenstein-Jensen medium (L-J 19 medium) and 7H9 broth, which are the commonly used media for drug susceptibility testing (DST) 20 for Mycobacterium tuberculosis. Methods: Rifampicin degradation in stock solution, 7H9 broth, 21 L-J medium, and during the inspissation process for L-J medium preparation was serially 22 monitored by hi...
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The photochemical reactions of methanolic nalidixic acid (NAL) solution in the absence and in the presence of air have been investigated using 300 nm UV light. From the reactions, 1-ethyl-7-methyl-4-oxo-4-hydro-1,8naphthyridine (EMDN), formic acid, and formaldehyde are produced. In the presence of air, hydrogen peroxide is also detected along with the products listed above. The presence of oxyg...
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Using two different liquid media and one conventional solid medium, a total of 57 mycobacterial isolates (Mycobacterium tuberculosis, n = 55; nontuberculous mycobacteria, n = 2) were recovered from 377 clinical specimens. The rates of recovery of M. tuberculosis were 96. 4% with the BACTEC MGIT 960 liquid medium, 92.7% with BACTEC 12B liquid medium, and 81.8% with the Löwenstein-Jensen (LJ) med...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1965
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.90.3.829-829.1965