N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage
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چکیده
منابع مشابه
N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage.
The posttranslational modification of histone and other chromatin proteins has a well recognized but poorly defined role in the physiology of gene expression. With implications for interfering with these epigenetic mechanisms, we now report the existence of a relatively abundant secondary modification of chromatin proteins, the N(6)-formylation of lysine that appears to be uniquely associated w...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2006
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0606775103