منابع مشابه
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
Toxoplasma gondii is a protozoan parasite that can damage the human brain and eyes. There are no curative medicines. Herein, we describe our discovery of N-benzoyl-2-hydroxybenzamides as a class of compounds effective in the low nanomolar range against T. gondii in vitro and in vivo. Our lead compound, QQ-437, displays robust activity against the parasite and could be useful as a new scaffold f...
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^ d jw0j (w0) + ^ d jw1j (w1) 2 + E(jwj + 1) = d 0 (w0) + d 0 (w1) 2 so d 0 obeys the average law (without conservation). Proof.[of Theorem 19] Note the d 0 constructed in Theorem 18 is generally not conservative. We will parallel Theorem 4, by constructing a slothful two-sided quasipolynomially precise cover. The construction of a conservative cover from a slothful cover preserves two-sided qu...
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Let $S_n$ be the symmetric group on the set $[n]={1, 2, ldots, n}$. For $gin S_n$ let $fix(g)$ denote the number of fixed points of $g$. A subset $S$ of $S_n$ is called $t$-emph{transitive} if for any two $t$-tuples $(x_1,x_2,ldots,x_t)$ and $(y_1,y_2,ldots ,y_t)$ of distinct elements of $[n]$, there exists $gin S$ such that $x_{i}^g=y_{i}$ for any $1leq ileq t$ and additionally $S$ is called e...
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The title compound, C(11)H(9)N(3)O(2)S, crystallizes with two independent mol-ecules in the asymmetric unit. The central thio-urea core makes dihedral angles of -3.3 (3) and 0.6 (3)° with the furan carbonyl groups in each mol-ecule, whereas the pyridine ring is inclined by 4.63 (2) and 11.28 (7)°, respectively. The trans-cis geometry of the thio-urea fragment is stabilized by an intra-molecular...
متن کاملN-(2-Aminophenylsulfonyl)-N-(2-nitrophenylsulfonyl)methylamine
In the title mol-ecule, C(13)H(13)N(3)O(6)S(2), the two benzene rings form a dihedral angle of 28.59 (7)°. The crystal sructure exhibits weak inter-molecular N-H⋯O, C-H⋯O and C-H⋯N hydrogen bonds and π-π inter-actions [centroid-to-centroid distance = 3.899 (3) Å].
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2011
ISSN: 1600-5368
DOI: 10.1107/s1600536811003680