Myogenic Growth Factors Can Decrease Extraocular Muscle Force Generation: A Potential Biological Approach to the Treatment of Strabismus
نویسندگان
چکیده
منابع مشابه
Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus.
PURPOSE Future pharmacologic treatment of strabismus may be optimized if drugs that are less potentially toxic to patients can be developed. Prior studies have shown that direct injection of extraocular muscles (EOMs) with insulin growth factor or fibroblast growth factor results in significant increases in the generation of EOM force. The purpose of this study was to examine the morphometric a...
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15 صفحه اولIncreasing muscle strength as a treatment for strabismus: sustained release of insulin-like growth factor-1 in rabbit extraocular muscle.
PURPOSE Currently, no drug treatment is available for strengthening underacting extraocular muscles (EOM) in strabismus. We showed previously that single injections of insulin-like growth factor (IGF-1) result in significant but short-term increases in muscle force generation. This study examined the effects of sustained release of IGF-1 on force generation in rabbit superior rectus muscles. ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2008
ISSN: 1552-5783
DOI: 10.1167/iovs.07-0600