Myocardial post-conditioning with Danshen-Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCε/mKATP-mediated pathway in rats
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Myocardial post-conditioning with Danshen-Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCε/mKATP-mediated pathway in rats
BACKGROUND Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the effect of DG post-conditioning on isoproterenol (ISO)-induced myocardial injury in rats. METHODS ISO was injected intraperitoneally (200 mg/kg) to induce acute (2-6 hours) m...
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ژورنال
عنوان ژورنال: Chinese Medicine
سال: 2011
ISSN: 1749-8546
DOI: 10.1186/1749-8546-6-7