Myocardial Coefficient of Oxygen Utilization

Myocardial coefficient of oxygen utilization.

THE COEFFICIENT of oxygen utilization is defined as the arteriovenous difference in oxygen concentration divided by the concentration of oxygen in the arterial blood. Multiplication of the ratio by 100 converts the coefficient into the per cent of arterial oxygen which is removed by the tissue. The term "oxygen extraction ratio" is frequently used as a synonym. Conflicting reports have appeared...

Delineation of myocardial oxygen utilization with carbon-11-labeled acetate.

Although positron-emission tomography (PET) with labeled fatty acid delineates infarct size and permits qualitative assessment of fatty acid utilization, quantification of oxidative metabolism is limited by complex alterations in the pattern of utilization of fatty acid during ischemia and reperfusion. Because metabolism of acetate by myocardium is less complex than that of glucose or palmitate...

The Coefficient of Resource Utilization

The Hemodynamic Effects of Drugs on Myocardial Oxygen Use

The circulatory responses to high equinalgesic doses of morphine are compared with those of pethidin. The decrease in mean arterial blood pressure in case of morphine was 28p.c., with a paralleled and identical de­crease in total peripheral resistance and no negative inotropic effects.  Pethidine decreased blood pressure 54p.c., as a result of peripheral vasodilation of 46p.c. and a sharp drop...

MYOCARDIAL ISCHEMIA Delineation of myocardial oxygen utilization with carbon - 11 - labeled acetate

Although positron-emission tomography (PET) with labeled fatty acid delineates infarct size and permits qualitative assessment of fatty acid utilization, quantification of oxidative metabolism is limited by complex alterations in the pattern of utilization of fatty acid during ischemia and reperfusion. Because metabolism of acetate by myocardium is less complex than that of glucose or palmitate...