Mycosynthesis of Zinc Oxide Nanoparticles Coated with Silver using Ganoderma lucidum (Curtis) P. Karst and Its Evaluation of In Vitro Antidiabetic and Anticancer Potential

Nanotechnology is an evolving interdisciplinary field of research interspersing material science and nanobiotechnology. Nanoparticles are studied extensively for their specific catalytic, magnetic, electronic, optical, antimicrobial, theranostic, diagnosis, wound healing, anti-inflammatory properties. ZnO nanoparticles (NPs) have many applications owing to unique characteristics, which include low cost, nontoxicity, abundance in nature, the ability prepare compounds with varying morphologies having different The main aim study biosynthesis coated silver from aqueous extract Ganoderma lucidum (Curtis) P. Karst evaluate its antidiabetic potential by performing alpha-glucosidase inhibition alpha-amylase assays anticancer cytotoxicity (MTT) assay against human breast cancer MDA-MB 231 cell lines. Ag was characterized UV–vis spectroscopy, Fourier transform infrared energy dispersive X-ray analysis, scanning electron microscope, transmission microscopy. An increasing concentration biosynthesized produces strong activity through enzyme effect reduction viability. present recommended that “Biological” method biological nanoparticle production a promising approach allows synthesis conditions, requirements costs. In future, mycosynthesized might be used medical arena treat prevent diseases.