Mycobacterium avium rough-to-smooth colony conversion resulting from growth in Tween 80 without presence of type-specific glycopeptidolipid antigens

Structure of the Specific Oligosaccharides from the Glycopeptidolipid Antigens of Serovars in the Mycobacterium auium-Mycobacterium

The specific oligosaccharide units of the C-mycosidic glycopeptidolipid antigens from serovarieties in the Mycobacterium avium-Mycobacterium intracellulare-Mycobacterium scrofulaceum complex were liberated as oligosaccharide alditols by treatment of the glycopeptidolipids with alkaline borohydride. The complete structures of the oligosaccharide alditols have been derived from their ‘H-NMR spect...

SERA FROM SYPIllLI ATIC PATIENTS CROSS REACT WITH SPECIFIC GLYCOPEPTIDOLIPID AND WHOLE LIPID EXTRACT OF MYCOBACTERIUM AVIUM COMPLEX IN AN ANTICARDI OLIPIN ANTIBODY TEST

Serodiagnosis of pulmonary disease due to Mycobacterium avium complex with an enzyme immunoassay that uses a mixture of glycopeptidolipid antigens.

It is difficult to distinguish pulmonary disease due to Mycobacterium avium complex (MAC) from that due to other mycobacteria, such as Mycobacterium tuberculosis and Mycobacterium kansasii. We developed an enzyme immunoassay (EIA) for diagnosis of MAC pulmonary diseases that uses glycopeptidolipid (GPL) antigens specific for MAC, and we used it for diagnosis in immunocompetent patients. The mea...

Preparation and Purification of Polyclonal Antibodies against Mycobacterium Avium Paratuberculosis Antigens in Rabbit

Background and Objective: Johne’s disease is the chronic granulomatous enteritis of ruminants, and a major health hazard worldwide. In recent years, researchers have focused on mycobacterium avium subsp. paratuberculosis (MAP) antigens in diagnostic tests. Identification of antibodies against MAP antigens is, therefore, effective for the diagnosis or preparation of vaccine. The aim of this stud...

Isolation and expression of a gene cluster responsible for biosynthesis of the glycopeptidolipid antigens of Mycobacterium avium.

Bacteria within the Mycobacterium avium complex are prominent in the environment and are a source of serious disseminated infections in patients with AIDS. Serovars of the M. avium complex are distinguished from all other mycobacteria and from one another by the presence of highly antigenic glycolipids, the glycopeptidolipids, on their surfaces. A genomic library of DNA from serovar 2 of the M....