منابع مشابه
A Polymorphism in the Chitotriosidase Gene Associated with Risk of Mycetoma Due to Madurella mycetomatis Mycetoma–A Retrospective Study
BACKGROUND Madurella mycetomatis is the most prevalent causative agent of eumycetoma in Sudan, an infection characterized by the formation of grains. Many patients are exposed to the causative agent, however only a small number develop infection. M. mycetomatis contains chitin in its cell wall, which can trigger the human immune system. Polymorphisms in the genes encoding for the chitin-degradi...
متن کامل[Madurella mycetomatis antigen for the serodiagnosis of mycetoma].
The aim of this work was to standardize metabolic and cytoplasmic Madurella mycetomatis antigen to be applied in the immunodiagnosis of mycetoma. Growth curves were established growing the mold in two broth media with weekly measures of protein and carbohydrate levels and of dry weight. Sera from immunized rabbits and patient's sera were used in immunoprecipitation to test the antigens. Three w...
متن کاملSubcutaneous facial mycosis in a child due to Madurella mycetomatis.
Mycetoma is a chronic, granulomatous, subcutaneous, inflammatory disease caused by true fungi (eumycetoma) or filamentous bacteria (actinomycetoma). Eumycetoma usually affects adult males involving limbs and other exposed body parts. Children represent the least commonly encountered age group with this disease. A case of subcutaneous facial mycosis due to Madurella mycetomatis in a three year o...
متن کاملMadurella mycetomatis Is Highly Susceptible to Ravuconazole
The current treatment of eumycetoma utilizing ketoconazole is unsatisfactory because of high recurrence rates, which often leads to complications and unnecessary amputations, and its comparatively high cost in endemic areas. Hence, an effective and affordable drug is required to improve therapeutic outcome. E1224 is a potent orally available, broad-spectrum triazole currently being developed fo...
متن کاملGenome Sequence of Madurella mycetomatis mm55, Isolated from a Human Mycetoma Case in Sudan
We present the first genome sequence for a strain of the main mycetoma causative agent, Madurella mycetomatis This 36.7-Mb genome sequence will offer new insights into the pathogenesis of mycetoma, and it will contribute to the development of better therapies for this neglected tropical disease.
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ژورنال
عنوان ژورنال: IDCases
سال: 2020
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2020.e00857