Mutational landscape of chronic myeloid leukemia: more than a single oncogene leukemia
نویسندگان
چکیده
منابع مشابه
Unusual ophthalmic manifestation in chronic myeloid leukemia: A case report
Background: Chronic myeloid leukemia (CML) is a myeloproliferative hematopoietic malignancy with a heterogeneous proliferation of hematopoietic cells in the bone marrow. The ocular manifestations are rare symptoms of CML. In this case report, a CML patient with retinal hemorrhage is reported as an uncommon symptom. Case presentation: A 35-year-old man was referred due to decreased right eye vi...
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Sequencing studies have been instrumental in understanding the genetic basis of chronic lymphocytic leukemia (CLL). Our recent whole-genome sequencing study focusing on lower cytogenetic risk CLL demonstrated that CLL mutations can be attributed to 3 key mutational processes-2 types of activation induced-cytidine deaminase (AID) signatures and an aging signature-that operate at different times ...
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ژورنال
عنوان ژورنال: Leukemia & Lymphoma
سال: 2021
ISSN: 1042-8194,1029-2403
DOI: 10.1080/10428194.2021.1894652