Mutagenicity of octane and tetrasodium pyrophosphate in bacterial reverse mutation (Ames) test
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چکیده
منابع مشابه
Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.
The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quer...
متن کاملLack of Mutagenicity Potential of Periploca sepium Bge. in Bacterial Reverse Mutation (Ames) Test, Chromosomal Aberration and Micronucleus Test in Mice
OBJECTIVES The root barks of Periploca sepium Bge. (P. sepium) has been used in traditional Chinese medicine for healing wounds and treating rheumatoid arthritis. However, toxicity in high-doses was often diagnosed by the presence of many glycosides. The potential mutagenicity of P. sepium was investigated both in vitro and in vivo. METHODS This was examined by the bacterial reverse mutation ...
متن کاملActivity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays.
Eight quinolones were examined for their bacterial mutagenicity in the Ames Salmonella TA102 assay and for their effects in other bacterial genotoxicity assays. In the quantitative Ames plate incorporation assay, all eight quinolones induced His+ deletion reversion in Salmonella tester strain TA102, with maximum reversion observed at about two to eight times the MIC. The quinolones also induced...
متن کاملMutagenicity of glutathione and cysteine in the Ames test.
Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine independence. Glutathione was also activated by kidney postmitochondrial supernatant but not by liver preparations. Hence, important endogenous compounds of mammals are positive in the most commonly used short-term...
متن کاملB. 13/14. Mutagenicity : Reverse Mutation Test Using Bacteria
only European legislation published in the paper editions of the Official Journal of the European Communities is deemed authentic. This text was prepared from the draft protocol sent for approval to the Member States. Minor editorial differences may exist between this version and the one published in the paper edition of the Official Journal. Care has been taken to ensure correctness of the tex...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2010
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.35.555