Mutagenicity of Analgesics, Their Derivatives, and Anti-inflammatory Drugs with S-9 Mix of Several Animal Species.
نویسندگان
چکیده
منابع مشابه
Mutagenicity of analgesics, their derivatives, and anti-inflammatory drugs with S-9 mix of several animal species.
An investigation was undertaken to determine whether analgesics and their derivatives (13 compounds), and anti-inflammatory drugs (4 compounds) had mutagenicity. Rec-assay was used to clarify specific DNA-damaging properties, and the Ames test was used to find back-mutations, using S-9 fractions obtained from the liver of 4 animal species pretreated with polychlorobiphenyl. In the Rec-assay, sa...
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ژورنال
عنوان ژورنال: The Journal of Nihon University School of Dentistry
سال: 1992
ISSN: 1884-2984,0029-0432
DOI: 10.2334/josnusd1959.34.183