منابع مشابه
Coxsackievirus B3 infection in human leukocytes and lymphoid cell lines.
Although coxsackie B viruses (CBVs) are known to cause viremia during acute infection, the role of the blood cells as a target for virus replication is poorly understood. We have analyzed the susceptibility of human peripheral blood mononuclear cells (PBMCs), granulocytes, bone marrow (BM) cells, and lymphoid cell lines to coxsackievirus B3 infection. Lymphoid cell lines with B- and T-cell char...
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The cytotoxic effect of fresh lymphocytes on tumor cells in vitro has been reported by numerous investigators, one of the earliest being Humble et al. (1). The cytotoxic activity of fresh lymphocytes for primary cultures of tumor cells has been evaluated by counting the surviving tumor cells (2) or by calculating the percentage reduction in tumor cell colonies as compared to control primary cul...
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Besides their regulatory role in embryogenesis, homeobox (HOX) genes are expressed in a specific manner in hematopoietic cell lineages, implying a role in the molecular regulation of hematopoiesis. Some HOX C cluster genes are found to be expressed in lymphoid cells of mice and humans. Their function and expression in normal hematopoiesis are still largely unknown. We have studied the mRNA expr...
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متن کاملNatural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells.
Natural polyreactive IgM autoantibodies, encoded by unmutated germline Ig V genes, represent a major fraction of the normal circulating IgM repertoire. We have previously shown that therapeutic preparation of pooled IgM exerts immunomodulatory effects as assessed by in vitro and in vivo studies. Here, we show that the IgM preparation induces cell death in lymphoblastoid cell lines and in human ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1977
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197704000-00497